Chemistry & Biochemistry

Beginning with the interwar period and concluding with the defeat of Japan, this book examines diplomatic, legal, military, and social issues the Western Allies (Great Britain, the United States, and Canada) confronted when they faced the threat and considered the use of chemical weapons during World War II"-- Provided by publisher.

"The volume investigates to what extent the international and European Union legal frameworks applicable to Chemical, Biological and Radio-Nuclear (CBRN) events are adequate to face current challenges."

Presenting both a panoramic introduction to the essential disciplines of drug discovery for novice medicinal chemists as well as a useful reference for veteran drug hunters, this book summarizes the state-of-the-art of medicinal chemistry. It covers key drug targets including enzymes, receptors, and ion channels, and hit and lead discovery. The book hen surveys a drug's pharmacokinetics and toxicity, with a solid chapter covering fundamental bioisosteres as a guide to structure-activity relationship investigations.